Exosome Stem Cell

What is Exosome Stem Cell?

Exosomes are very small vesicles with a diameter of 30-150 nanometers, which have a lipid membrane and carry genetic information, growth factors and proteins, through which our cells release into our body. They are 1/1000 the size of a cell.

Exosomes: provide intercellular communication and carry molecules that are important regulators of intracellular information between nearby and distant cells.

Exosomes have high potential in the field of regenerative medicine: cell renewal and repair.

What does Exosome Stem Cell do?

The main function of exosomes is to improve responses to stimuli and intercellular communication by releasing signaling molecules.

Exosomes; can change cell behavior by transferring some genetic information, proteins and receptors between cells. Thanks to these properties, they are effective in cell proliferation and tissue regeneration.

Exosomes; have an inflammatory-reducing effect by suppressing inflammatory proteins, suppressing anti-inflammatory proteins and stimulating anti-inflammatory proteins.

Exosomes; show regenerative activity by stimulating the proliferation and migration of fibroblasts, endothelial cells, keratinocytes and specific endogenous progenitor cells (progenitor cells) to the damaged area.

Studies have shown that exosomes obtained from mesenchymal stem cells reduce apoptosis (programmed cell death) that occurs in tissues damaged as a result of disease or injury.

Exosomes; ensure tissue renewal by increasing the normal cross-collagen bond structure. It reduces scars and provides healing closer to normal tissue.

How Many Sessions Are Exosome Stem Cell Treatment Applied?

Exosome treatment, which will be applied to the desired area in line with the decision of our clients and our doctor, is applied in a single session. After this procedure is applied once, the desired result is achieved.
Exosome is stored sterile in our clinic as a homogeneous suspension, and about 30 minutes before application, the patient’s skin is cleaned and a local numbing cream is applied. After the procedure is applied to the dermis layer by injection, the patient can immediately continue his social or business life.

When Does Exosome Stem Cell Treatment Work?

No pressure or liquid treatment should be applied to the skin for 24 hours after application. It is appropriate to take a warm shower after 24 hours. Make-up etc. for 72 hours. Cosmetic substances and procedures should not be applied to the skin. Aesthetic procedures should be performed after 3 weeks. The effect is quickly seen immediately after injection. The final result is achieved within 4-6 weeks after the injection, when allogeneic fibroblasts settle in the target area, begin to produce elastin and collagen, and the skin gradually regains its vitality. As a result, the effects of Alloblast application begin to be seen very soon after the application, within about a month. Results are seen 4 times faster than Fibrocell, which is made from the person’s own tissue. Because the tissues used in Alloblast stem cell treatment are younger. They are healthier, more dynamic cells that have not been exposed to any negative environmental factors until they are taken into tissue culture.

What is ExoStem Stem Cell?

ExoStem; obtained by purifying the culture medium of mesenchymal stem cells (MSCs) obtained from newborn umbilical cord tissue with special processes, containing many growth factors and having the capacity to regulate the cellular and biochemical events that play a role in skin rejuvenation / cell renewal. They are protein vesicles.

Mesenchymal Stem cell derived exosomes; Preferably used in regenerative medicine. These cells are excellent regenerative cells due to their multipotent nature, so exosomes derived from Mesenchymal Stem Cells are superior to other exosome products.

Physiological effects of exosomal growth factors in ExoStem; It can be used to stimulate healing, regenerate collagen in aging and damaged skin, and reduce inflammation.

ExoStem; It has the potential to accelerate healing, improve skin texture, reduce scarring, stimulate hair growth, and shorten recovery time after cosmetic procedures.

How to Obtain ExoStem Stem Cells

Cells obtained from newborn umbilical cord tissue are grown in special culture dishes with cell-specific nutrients. Dead cell residues are removed from the culture medium of the replicated cells. After the pre-treatment steps, exosomes are isolated by high-speed spinning using an ultracentrifuge.

After the obtained exosomes pass quality control tests, they are turned into product vials and stored under appropriate conditions.

ExoStem; is a cell-free product isolated from MSCs obtained from umbilical cord tissue. Umbilical cord tissues processed in Stembio laboratories are accepted in accordance with the donor criteria. The suitability of the donor’s Serology test results is checked in line with the acceptance criteria (HIV, ANTI-hBC, HBSaG, HCV, SYPHILIS, CMV IgC).

What are the Clinical Uses of Exosomes?

Other Areas Where MSC Exosomes Can Be Used in Dermatology

• Blemish Treatment
• Acne Scar Treatments
• Atopic Dermatitis/Eczema
• Wound Healing
• Burn Treatment

Effects of MSC Exosomes on Skin

• Stimulates proliferation and proliferation of fibroblast cells.
• Increases angiogenesis.
• Increases collagen extracellular matrix and storage.
• Regulates inflammation and immune response.
• Regulates tissue remofeling reconstruction.

Effect of MKH Exosomes on Skin Rejuvenation (Anti-aging)

Stem cell-derived exosomes can be used to restore aging tissues of the body due to its regenerative ability.

Signs of aging occur due to the skin’s inability to renew itself, exosomes can help maintain skin elasticity and strength.

The Effect of MKH Exosomes on Hair Loss

It increases the number of hair follicles in the growth phase. It degenerates the thermal papilla cells that form hair follicles. In the early stages of Hair Loss, hair can regrow and regenerate in men and women by applying growth factors through exosome application.

A visible change can be seen within 1 or 2 months after the first application of exosome therapy, but the most significant changes are observed between 6 and 12 months.

Exosomes extend the hair growth cycle and do this by converting hair follicles in the resting phase (telogen phase) into the growth phase (anagen phase).

How Long Does Exosome Treatment Take?

Exosome stem cell treatment takes approximately 30 minutes. You can continue your daily life after the session.

What is the Price of Exosome Treatment?

You can meet with our doctor by making an appointment and get a price for Exosome Stem Cell Treatment according to the area to be applied. This meeting to determine the treatment and area to be applied is completely free of charge. Immediately after your consultation with our doctor, the most affordable price for Exosomal stem cell treatment will be revealed to you, our clients.